A Randomized, Controlled Trial of Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The purpose of this clinical trial is to determine if receiving magnesium sulfate as an adjunctive analgesic for prostate surgery is effective in reducing pain. Subjects will be randomized to receive magnesium or not receive it, as part of a standardized general anesthetic for prostate surgery. The primary objective is to demonstrate improved pain scores in patients receiving magnesium sulfate as an adjunctive analgesic during surgery. Secondary objectives include demonstrating reduced requirements for other opioids, reduced postoperative shivering, improved discharge home and adequate neuromuscular blockade reversal, measured by quantitative train of four monitoring.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 and older.

• Undergoing a robotic prostatectomy under general anesthesia.

• Is willing and able to provide consent to participate in the study.

Locations
United States
New York
NYU Langone Health
RECRUITING
New York
Contact Information
Primary
Mark Nunnally, MD
nunnally@nyulangone.org
212-263-2087
Time Frame
Start Date: 2024-06-04
Estimated Completion Date: 2026-06
Participants
Target number of participants: 110
Treatments
Experimental: Magnesium
Patients in the first group will receive 2 grams magnesium sulfate at the end of surgery as a bolus over approximately 10 minutes intravenously.
No_intervention: No magnesium
Patients in the second group will receive no magnesium.
Related Therapeutic Areas
Sponsors
Leads: NYU Langone Health

This content was sourced from clinicaltrials.gov