Sacral Nerve Stimulation Clinical Trials

Clinical trials related to Sacral Nerve Stimulation Procedure

Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Electrical stimulation of the sacral nerve can help with bladder problems and pelvic pain but researchers don't understand exactly how the stimulation helps. The goal of this study is to examine signals evoked during sacral neuromodulation (SNM or electrical stimulation of the sacral nerve) and their relationship to the selection of stimulation parameters that improve pelvic function symptoms. This study uses SNM parameters based on visual-motor responses (VMR) or sacral evoked responses (SER). It is investigating how the parameter selection impacts change in bladder function.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Determined by the research team to be fully eligible to receive a sacral neuromodulation implant at a sacral nerve as part of their normal clinical care for overactive bladder (OAB).

• Adult (18 or older), capable of providing own informed consent and communicating clearly with research team.

• Capable of speaking, reading, and understanding English, as all study questionnaires are standardized assessments only available in English.

Locations
United States
Michigan
University of Michigan
RECRUITING
Ann Arbor
Contact Information
Primary
Yike Liu
yikel@med.umich.edu
734-763-7104
Time Frame
Start Date: 2025-10-16
Estimated Completion Date: 2029-10
Participants
Target number of participants: 15
Treatments
Experimental: VMR followed by SER
SNM implants will use parameters selected based on visual-motor responses (VMRs) for four weeks followed by parameters selected based on sacral evoked responses (SERs) for four weeks.
Experimental: SER followed by VMR
SNM implants will use parameters selected based on sacral evoked responses (SERs) for four weeks followed by parameters selected based on visual-motor responses (VMRs) for four weeks.
Related Therapeutic Areas
Sponsors
Collaborators: Medtronic
Leads: University of Michigan

This content was sourced from clinicaltrials.gov