Real-time Lymphatic Channel Visualization Compared With Conventional Cervical Indocyanine Green Injection for Sentinel Lymph Node Mapping in Early-stage Endometrial Cancer

Status: Completed
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Endometrial cancer is the most common malignancy of the female genital tract. Standard treatment for early-stage disease includes hysterectomy, bilateral salpingo-oophorectomy, and lymph node assessment. Sentinel lymph node (SLN) mapping with indocyanine green (ICG) has become widely used as an alternative to systematic lymphadenectomy due to lower morbidity and high detection rates. This randomized clinical trial was designed to compare conventional cervical ICG injection with a modified technique, in which injection is continued until real-time lymphatic channels are visualized intraoperatively, for bilateral SLN detection in patients with clinical early-stage endometrial cancer undergoing robotic surgery.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
Locations
Other Locations
Turkey
Gökhan Demirayak
Istanbul
Time Frame
Start Date: 2021-07-13
Completion Date: 2025-09-15
Participants
Target number of participants: 80
Treatments
Experimental: Experimental injection
Cervical indocyanine green injections until real-time visualization of the afferent lymphatic channels bilaterally.
Active_comparator: Standart injection
Cervical indocyanine green injections group
Sponsors
Leads: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

This content was sourced from clinicaltrials.gov