Comparative Evaluation of Soaked Pharyngeal Packing Agents in Septoplasty Procedure: Impact on Postoperative Outcomes
Status: Recruiting
Location: See location...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
Postoperative sore throat (POST) is a frequent and distressing complication after general anesthesia with endotracheal intubation, particularly in nasal surgery for example, functional endoscopic sinus surgery, septoplasty, or septo-rhinoplasty, where pharyngeal packing is routine. While pharyngeal packs may reduce blood ingestion, they may exacerbate POST, warranting effective pharmacologic prophylaxis. This study assesses the efficacy of dexamethasone-soaked pharyngeal packs in reducing incidence of POST in patients undergoing elective septoplasty surgeries.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Adults aged 18 to 65 years,
• Both male and female,
• Classified as American Society of Anesthesiologists (ASA) physical status I to III, and
• Scheduled for elective septoplasty.
Locations
Other Locations
Egypt
Assiut University
RECRUITING
Asyut
Contact Information
Primary
Omar Makram Soliman, MD
omar@aun.edu.eg
00201065491191
Time Frame
Start Date: 2026-03-20
Estimated Completion Date: 2026-06-04
Participants
Target number of participants: 90
Treatments
Placebo_comparator: Placebo
A sterile, non-absorbable gauze strip that will be between 30 and 50 cm² in size and with a retrieval thread for atraumatic removal made, then for 30 seconds, the gauze is submerged in 25 ml of normal saline solution
Active_comparator: Dexamethasone
A sterile, non-absorbable gauze strip that will be between 30 and 50 cm² in size and with a retrieval thread for atraumatic removal made, then for 30 seconds, the gauze is submerged in 8 mg dexamethasone and 25 ml of normal saline solution
Related Therapeutic Areas
Sponsors
Leads: Assiut University