Thrombus Aspiration in Primary Percutaneous Coronary Intervention for STEMI Patients With High Thrombus Burden
Status: Recruiting
Location: See all (50) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is a prospective, multicenter, open-label, randomized, controlled, parallel group study, in which ST-segment Elevation Myocardial Infarction (STEMI) patients with high thrombus burden(TIMI thrombus grade ≥3) are included. Patients are randomized to be treated with or without manual thrombus aspiration(TA) during primary percutaneous coronary intervention(PPCI) by a ratio of 1:1.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years;
• STEMI patients undergoing primary PCI within 12 hours after the onset of symptoms;
• High thrombus burden after guidewire passes the lesion (TIMI thrombus grade ≥3);
• Informed consent must be voluntary;
Locations
Other Locations
China
The Second Xiangya Hospital of Central South University
NOT_YET_RECRUITING
Changsha
The Third Xiangya Hospital of Central South University
RECRUITING
Changsha
Sichuan Provincial People's Hospital
NOT_YET_RECRUITING
Chengdu
West China Hospital
NOT_YET_RECRUITING
Chengdu
First People's Hospital of Foshan
RECRUITING
Foshan
First People's Hospital of Shunde (Affiliated Hospital at Shunde, Southern Medical University)
RECRUITING
Foshan
The Second People's Hospital of Nanhai District
RECRUITING
Foshan
Fujian Provincial Hospital
NOT_YET_RECRUITING
Fuzhou
GanZhou Municopal Hospital
NOT_YET_RECRUITING
Ganzhou
Shangyou Hospital
RECRUITING
Ganzhou
Guangdong Provincial Hospital of traditional Chinese Medicine
NOT_YET_RECRUITING
Guangzhou
Guangdong Provincial People's Hospital
RECRUITING
Guangzhou
Guangzhou General Hospital of Guangzhou Military Command
NOT_YET_RECRUITING
Guangzhou
Guangzhou Panyu Central Hospital
NOT_YET_RECRUITING
Guangzhou
Huadu District People's Hospital of Guangzhou
NOT_YET_RECRUITING
Guangzhou
Huangpu Division of The First Affiliated Hospital, Sun Yat-sen University
NOT_YET_RECRUITING
Guangzhou
Nanfang Hospital
NOT_YET_RECRUITING
Guangzhou
The First Affiliated Hospital of Guangzhou Medical University
NOT_YET_RECRUITING
Guangzhou
The first Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Guangzhou
The Second Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Guangzhou
Zhujiang Hospital of Southern Medical University
NOT_YET_RECRUITING
Guangzhou
Guilin people's Hospital
NOT_YET_RECRUITING
Guilin
Hainan People's Hospital
NOT_YET_RECRUITING
Haikou
The Second Clinical College of Hainan Medical University
NOT_YET_RECRUITING
Haikou
Huizhou Third People's Hospital
NOT_YET_RECRUITING
Huizhou
Jiangmen Central Hospital
RECRUITING
Jiangmen
Kaiping Central Hospital
RECRUITING
Kaiping
Kashgar first people's Hospital
RECRUITING
Kashgar
Yan'an Hospital of Kunming City
NOT_YET_RECRUITING
Kunming
Maoming People's Hospital
NOT_YET_RECRUITING
Maoming
The Second Affiliated Hospital of Shantou university Medical College
RECRUITING
Shantou
Yue Bei People's Hospital
RECRUITING
Shaoguan
Shaoxing people's Hospital
NOT_YET_RECRUITING
Shaoxing
Peking University Shenzhen Hospital
NOT_YET_RECRUITING
Shenzhen
Shenzhen Bao'an District People's Hospital
RECRUITING
Shenzhen
Shenzhen People's Hospital
RECRUITING
Shenzhen
The Eighth Affiliated Hospital, Sun Yat-Sen University
RECRUITING
Shenzhen
Taishan people's Hospital
RECRUITING
Taishan
The First Affilicated Hospital of Xinjiang Medical University
NOT_YET_RECRUITING
Ürümqi
Affiliated Hospital, Weifang Medical University
RECRUITING
Weifang
The First Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITING
Wenzhou
Wuhan Asia Heart Hospital
NOT_YET_RECRUITING
Wuhan
The first Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITING
Xi’an
Nanxiong people's Hospital
RECRUITING
Xiongzhou
People's Hospital of Yangjiang City
RECRUITING
Yangjiang
The Second Affiliated Hospital of Guangdong Medical University
NOT_YET_RECRUITING
Zhanjiang
Sihui people's Hospital
RECRUITING
Zhaoqing
Zhongshan People's Hospital
RECRUITING
Zhongshan
The Fifth Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Zhuhai
Zhuhai people's Hospital
NOT_YET_RECRUITING
Zhuhai
Contact Information
Primary
Pengcheng He, MD
drhepengcheng@aliyun.com
86-13829730152
Time Frame
Start Date: 2020-08-30
Estimated Completion Date: 2027-04-30
Participants
Target number of participants: 3838
Treatments
Experimental: Thrombus aspiration
Upfront manual thrombus aspiration followed by PCI
Active_comparator: PCI Alone
PCI without upfront manual thrombus aspiration
Related Therapeutic Areas
Sponsors
Leads: Guangdong Provincial People's Hospital
Collaborators: The Affiliated Shunde Hospital of Jinan University, Jiangmen Central Hospital, Meizhou Traditional Chinese Medicine Hospital, Nanning Second People's Hospital, Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen Third People's Hospital, Third Affiliated Hospital, Sun Yat-Sen University, Shenzhen Longhua District Central Hospital, People's Hospital of Yingde City, Sihui City People's Hospital, Guangxi Zhuang Autonomous Region Nationalities Hospital, Guangzhou Hospital of integrated Traditional and West Medicine, Chaozhou Central Hospital, Dongguan People's Hospital, Luhe County People's Hospital, Taishan People's Hospital, Weifang Medical University, Southern Medical University, China, Shantou Central Hospital, Guangning People's Hospital, Kaiping Central Hospital, Xiaolan People's Hospital of Zhongshan, Heyuan Shenhe People's Hospital, Nanhai District People's Hospital, The First People's Hospital of Kashgar Erea, The Third Affiliated Hospital of Guangzhou Medical University, The Fourth People's Hospital of Chenzhou, People's Hospital of Dapu County, Second Affiliated Hospital of Shantou University Medical College, The Second People's Hospital of Foshan, Longgang District People's Hospital of Shenzhen, Shenzhen Baoan District Traditional Chinese Medicine Hospital, The First Dongguan Affiliated Hospital of Guangdong Medical University, People's Hospital of Xinjiang Uygur Autonomous Region, Shenzhen People's Hospital, Tongxiang First People's Hospital, Qingyuan People's Hospital, Wuzhou Gongren Hospital, The Second Affiliated Hospital of Dalian Medical University, The First Affiliated Hospital of Gannan Medical College, Huaiji People's Hospital, Luohe Central Hospital, Yangchun People's Hospital, Liuzhou Municipal Liutie Central Hospital, Puyang People's Hospital, Zhongshan Hospital Of Traditional Chinese Medicine, Chaoshan Hospital, the First Affiliated Hospital of Jinan University, Bobai County People's Hospital, Guangxi, Tongliao People's Hospital, Chen Zhou 3RD People's Hospital, Linying County People's Hospital, Zhaoqing Gaoyao People's Hospital, Shenzhen Baoan District People's Hospital, The Second People's Hospital of Nanhai District of Foshan, People's Hospital of Nanxiong County, Yangjiang People's Hospital, The Third Xiangya Hospital of Central South University, First People's Hospital of Foshan, Lianzhou People's Hospital, Shangyou People's Hospital, Dafeng Hospital of Chaoyang District in Shantou City, Lianping Xian Ren Ming Yi Yuan, Foshan Sanshui District People's Hospital, Zhongshan People's Hospital, Guangdong, China, Yuebei People's Hospital