TACTIC Coronary Thrombus Aspiration With Cath Rx In Anterior Myocardial Infarction: A Randomized Control Trial.
The aim of this study is to evaluate the impact of sustained thrombectomy with INDIGO ASPIRATION SYSTEM using CAT RX versus no thrombectomy during primary percutaneous coronary intervention (PPCI) on microvascular obstruction and infarct size, as measured by cardiovascular magnetic resonance (CMR) between 3 and 5 days post PPCI, in patients with anterior STEMI
• Age \>18 and \<75 years old
• Acute anterior STEMI with ≥2 mm in two (2) or more contiguous anterior leads or ≥4 mm total ST-segment deviation sum in the anterior leads V1-V4 AND anterior wall motion abnormality noted on a diagnostic quality left ventriculogram or echocardiogram
• Culprit lesion proximal or mid LAD at coronary angiography
• TIMI thrombus grading \> 3 or TIMI flow 0 after guidewire crossing the lesion.
• Patient presents to the hospital between 1 - 6 hours of ischemic pain onset
• Patient indicated for primary percutaneous coronary intervention (PPCI)