Protective Effect of Indocyanine Green Fluorescence Imaging Technology on Parathyroid Glands During Total Thyroidectomy

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Accurate identification and evaluation of the parathyroid glands (PGs) intraoperatively is critical to reduce the incidence of postoperative hypoparathyroidism after total thyroidectomy. Near-infrared fluorescence imaging (NIFI), including the autofluorescence (AF) and indocyanine green fluorescence (ICGF) imaging, is a promising technique to protect PGs. This study aimed to assess whether the combined use of AF and ICGF could reduce the incidence of postoperative hypoparathyroidism and improve the identification and evaluation of PGs during total thyroidectomy.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Male or female patients, aged 18 years and above

• Scheduled for elective total or hemi thyroidectomy

• Normal liver and renal function

• No known hypersensitivity for iodine or ICG

• Able to understand the nature of the study procedures

• Willing to participate and give written informed consent

Locations
Other Locations
China
Shandong Linglong Yingcheng Hospital
RECRUITING
Yantai
Contact Information
Primary
Xuan Qiu, MD
qiuxuan100@163.com
8618354280081
Backup
Ni Wang, MD,PD
wangni1989@163.com
8618705353551
Time Frame
Start Date: 2024-02-01
Estimated Completion Date: 2025-06-30
Participants
Target number of participants: 200
Treatments
Experimental: Indocyanine green group
Identification of parathyroid glands (PGs) Near-infrared (NIR) fluorescence visualization of PGs, for only experimental group
Active_comparator: Traditional surgery group
Conventional means of identification and assessment of PGs are mainly based on surgeon-dependent identification of their anatomical location and appearance (color, shape, etc.) by the naked eye.
Related Therapeutic Areas
Sponsors
Leads: Shandong Linglong Yingcheng Hospital

This content was sourced from clinicaltrials.gov