Percutaneous Vertebroplasty Using Rotary Cutter for Treating Bone Metastases

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Percutaneous vertebroplasty has been applied widely to treat bone metastases. The injected cement may strengthen the affected bone to prevent pathological fractures and relieve the pain. Moreover, the thermal reaction (70°C) due to polymerisation of cement also contributes to tumour destruction. The cement dose and diffusion pattern may be significant factors for the treatment efficacy, which can be affected by the inner pressure of the metastases. The investigators will apply a rotary cutter to destroy the structure of metastases to alleviate the pressure in the metastases. Then, more cement will be injected, which may effectively interdigitates with the surrounding bone and generate more thermo to kill the tumor cells.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Imaging-proven and pathology-proven metastases

• Intractable pain with neurologic dysfunction

Locations
Other Locations
China
960 Hospital of PLA
RECRUITING
Jinan
Contact Information
Primary
Min Li, M.D.
liminyingxiang@163.com
13953176057
Time Frame
Start Date: 2019-07-30
Estimated Completion Date: 2025-12
Participants
Target number of participants: 70
Treatments
Active_comparator: Conventional Percutaneous Vertebroplasty
The cement is injected after the successful puncture.
Experimental: Percutaneous Vertebroplasty with Rotary Cutter
The rotary cutter is applied to destroy the metastatic lesion before coment injection.
Related Therapeutic Areas
Sponsors
Leads: Li Min

This content was sourced from clinicaltrials.gov