Visual and Anatomical Outcomes of Autologous Tenon's Capsule Graft for Refractory Macular Holes

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This prospective interventional study evaluates the anatomical and functional outcomes of autologous Tenon's capsule grafting in patients with refractory full-thickness macular holes. Eligible patients include those with chronic large macular holes (\>400 µm) or persistent holes following prior pars plana vitrectomy with internal limiting membrane peeling and gas tamponade. Anatomical closure will be assessed using spectral-domain optical coherence tomography, and functional outcomes will be evaluated by best-corrected visual acuity over a 3-month follow-up period.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 years or older

• Refractory full-thickness macular hole defined as:

• Chronic macular hole \>400 µm, or

• Persistent macular hole following prior vitrectomy with ILM peeling and gas tamponade

• Clear ocular media and adequate fixation for OCT imaging

• Ability to provide informed consent

Locations
Other Locations
Egypt
Benha University
RECRUITING
Banhā
Contact Information
Primary
Ehab Mohamed Elsayed Saad Saad, lecturer
ehab.saad@fmed.bu.edu.eg
00201008418667
Time Frame
Start Date: 2025-12-14
Estimated Completion Date: 2026-06-03
Participants
Target number of participants: 20
Treatments
Other: Autologous Tenon's Capsule Graft
Procedure
Related Therapeutic Areas
Sponsors
Leads: Benha University

This content was sourced from clinicaltrials.gov