Visual and Anatomical Outcomes of Autologous Tenon's Capsule Graft for Refractory Macular Holes
This prospective interventional study evaluates the anatomical and functional outcomes of autologous Tenon's capsule grafting in patients with refractory full-thickness macular holes. Eligible patients include those with chronic large macular holes (\>400 µm) or persistent holes following prior pars plana vitrectomy with internal limiting membrane peeling and gas tamponade. Anatomical closure will be assessed using spectral-domain optical coherence tomography, and functional outcomes will be evaluated by best-corrected visual acuity over a 3-month follow-up period.
• Age 18 years or older
• Refractory full-thickness macular hole defined as:
• Chronic macular hole \>400 µm, or
• Persistent macular hole following prior vitrectomy with ILM peeling and gas tamponade
• Clear ocular media and adequate fixation for OCT imaging
• Ability to provide informed consent