3p deletion syndrome is a condition that results from a chromosomal change in which a small piece of chromosome 3 is deleted in each cell. The deletion occurs at the end of the short (p) arm of the chromosome. This chromosomal change often leads to intellectual disability, developmental delay, and abnormal physical features.
3p deletion syndrome is caused by deletion of the end of the small (p) arm of chromosome 3. The size of the deletion varies among affected individuals, ranging from approximately 150,000 DNA building blocks (150 kilobases or 150 kb) to 11 million DNA building blocks (11 megabases or 11 Mb). The deletion can include between 4 and 71 known genes. In some individuals, the deletion involves material near the end of the chromosome but does not include the tip (the telomere).
3p deletion syndrome is likely a rare disorder; at least 30 cases have been described in the scientific literature.
Most cases of 3p deletion syndrome are not inherited. The deletion occurs in one chromosome, most often as a random event during the formation of reproductive cells (eggs or sperm) or in early fetal development. In these cases, affected people have no history of the disorder in their family.
Chih-ping Chen practices in Taiwan. Chen is rated as an Elite expert by MediFind in the treatment of 3p Deletion Syndrome. They are also highly rated in 135 other conditions, according to our data. Their top areas of expertise are Cystic Hygroma, Chromosome 8p Deletion, Trisomy 12 Mosaicism, and Mosaic Trisomy 8.
Wayseen Wang practices in Puerto Rico. Wang is rated as a Distinguished expert by MediFind in the treatment of 3p Deletion Syndrome. They are also highly rated in 93 other conditions, according to our data. Their top areas of expertise are Trisomy 18, Chromosome 9p Deletion, Trisomy 12 Mosaicism, and Chromosome 22 Duplication.
Jun-wei Su practices in Taiwan. Su is rated as a Distinguished expert by MediFind in the treatment of 3p Deletion Syndrome. They are also highly rated in 21 other conditions, according to our data. Their top areas of expertise are Mosaicism, 3p Deletion Syndrome, Trisomy 2 Mosaicism, and Chromosome 3q Duplication.
Published Date: June 01, 2016Published By: National Institutes of Health
There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.