Characterisation of Intestinal Microbiota of Patients With Spondyloarthritis or Rheumatoid Arthritis

Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Observational
SUMMARY

The primary objective of the study aims to compare the biodiversity of intestinal microbiota between spondylarthritis (SPA) or rheumatoid arthritis (RA) patients and healthy volunteers, by microbiota DNA sequencing in order to further and respond the prior results, which suggested that there is a specific dysbiosis for each of the 2 diseases. A comparative analysis will allow to identify the biomarkers of the specific bacteria.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

⁃ Patients:

• Patient ⩾ 18 years;

• Diagnosed as spondyloarthritis (SpA) according ASAS classification, or rheumatoid polyarthritis according ACR/EULAR;

• Affiliated to a social security scheme;

• Have signed the written informed consent form.

⁃ Healthy control subjects:

• Adult women and men;

• Subjet free of chronic pathology;

• Affiliated to a social security scheme;

• Have signed the written informed consent form.

Locations
Other Locations
France
Service de Rhumatologie, Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris
RECRUITING
Boulogne-billancourt
Contact Information
Primary
Maxime BREBAN, MD, PhD
maxime.breban@aphp.fr
+ 33 1 49 09 56 72
Time Frame
Start Date: 2020-11-23
Estimated Completion Date: 2026-11
Participants
Target number of participants: 400
Treatments
patients with SPA
100 SPA patients
Healthy subjets
200 healthy subjets in control group
patients with RA
100 RA patients
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov