Prospective, Double Blind, Randomized Control Trial Comparing the Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to compare the efficacy of intra-articular corticosteroid injections versus platelet-rich plasma injections for non-operative treatment of primary glenohumeral osteoarthritis. The efficacy of intra-articular injections, outside of hyaluronic acid, for the treatment of glenohumeral OA is not known, yet these treatments are commonly used with hopes of providing patients with symptomatic relief that can hopefully delay or prevent the need for shoulder arthroplasty. This study will help elucidate the therapeutic benefit of corticosteroid and Platelet Rich Plasma (PRP) injections in this patient population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patient ≥18y.o. of age

• Primary glenohumeral arthritis (bone on bone or near bone on bone) that has been previously diagnosed on radiographs and clinical evaluation.

• Baseline pain level of VAS \>4

Locations
United States
Illinois
Rush University Medical Center
RECRUITING
Chicago
Contact Information
Primary
Carla M Edwards, PhD
carla_edwards@rush.edu
312.563.5735
Time Frame
Start Date: 2023-03-13
Estimated Completion Date: 2027-01
Participants
Target number of participants: 200
Treatments
Experimental: Corticosteroid Injection Group
80mg Depo-Medrol and 8cc Lidocaine ultrasound-guided intra-articular injection
Active_comparator: Platelet-Rich Plasma Injection Group
15cc blood draw in Arthrex Autologous Conditioned Plasma (ACP) kit and processed per manufacturer instructions Ultrasound-guided intra-articular injection of isolated PRP
Related Therapeutic Areas
Sponsors
Leads: Rush University Medical Center

This content was sourced from clinicaltrials.gov