THE USE OF FRESH PRP VS HA IN THE TREATMENT OF OSTEOARTHRITIS OF THE PATELLOFEMORAL JOINT Randomized Controlled Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of the study is to compare the 12-month clinical outcomes of patients with patellofemoral osteoarthritis undergoing infiltrative treatment with fresh PRP and HA

Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 65
Healthy Volunteers: f
View:

• Age between 30 and 65;

• Signs and symptoms of isolated patellofemoral osteoarthritis present in one or both knees;

• Radiographic signs of isolated patellofemoral osteoarthritis (according to Iwano et al stage 1-3 classification) or chondropathy (assessed on MRI) with K-L grade of the other compartments ≤ 2. \[PMID: 2302884 - PMID: 27979409\] ;

• Hemoglobin \> 11 g/dl; Platelet count \> 150,000 plt/mm3 (Recently performed CBC exam);

• No clinically significant electrocardiographic alterations (Recently performed ECG).

• Ability and consent of patients to actively participate in clinical follow-up;

• Signature of informed consent.

Locations
Other Locations
Italy
Istituto Ortopedico Rizzoli
RECRUITING
Bologna
Contact Information
Primary
Roberta Licciardi, MSc
roberta.licciardi@ior.it
0516366567
Backup
Alessandro Di Martino, MD
alessandro.dimartino@ior.it
Time Frame
Start Date: 2022-10-26
Estimated Completion Date: 2026-09
Participants
Target number of participants: 166
Treatments
Experimental: Autologous PRP injection
This group of patients will be treated with single intra-articular injection of Autologous PRP.
Active_comparator: HA injection
This group of patients will be treated with single intra-articular injection of Hyaluronic Acid (HA)
Related Therapeutic Areas
Sponsors
Leads: Istituto Ortopedico Rizzoli

This content was sourced from clinicaltrials.gov