Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS), a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questions it aims to answer are: * Are the treatments effective? * Is the surgical treatment more effective than the non-surgical treatment? Participants will receive surgical treatment (PIP joint denervation) or non surgical treatment (patient education plus exercise). Researchers will compare the non-surgical and surgical groups to see if pain, patient-reported function, quality of life, movement and grip strength differs between the groups.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥ 18 years.

• Chronic symptomatic osteoarthritis in the PIP-joint.

• Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV) (Kellgren \& Lawrence, 1957).

• Clinical signs of PIP-joint arthritis.

Locations
Other Locations
Sweden
Department of Hand Surgery, Södersjukhuset
RECRUITING
Stockholm
Contact Information
Primary
Elin Sward, MD, PhD
elin.sward@regionstockholm.se
+46812361000
Time Frame
Start Date: 2023-09-25
Estimated Completion Date: 2029-07-15
Participants
Target number of participants: 90
Treatments
Active_comparator: Surgical treatment
PIP joint denervation is performed through a volar approach.
Active_comparator: Non-surgical treatment
An education and exercise program.
Related Therapeutic Areas
Sponsors
Collaborators: Stockholm South General Hospital
Leads: Karolinska Institutet

This content was sourced from clinicaltrials.gov