The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral Total Knee Arthroplasty: a Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This interventional study aims to compare the effectiveness of local multimodal drug periarticular injection in TKA patients with the standard pain control regime that includes opioids, NSAIDs, and other analgesics. The main questions The investigators strive to answer are: Is there a significant difference in the severity of pain and functional outcomes when applying periarticular injections? Are there any increased complications when applying the periarticular injections?
Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 85
Healthy Volunteers: t
View:
• all patients with end-stage arthritis of the knee going primary unilateral total knee arthroplasty.
Locations
Other Locations
Syrian Arab Republic
Damascus university
RECRUITING
Damascus
Contact Information
Primary
jaber ibrahim, MD PHD
drjaberhibrahim@gmail.com
944411241
Time Frame
Start Date: 2024-03-01
Estimated Completion Date: 2025-11-30
Participants
Target number of participants: 80
Treatments
Experimental: TKA with pain management by multimodal periarticular injection.
Patients going TKA and getting an injection of a mixture of 20ml of low body weight bupivacaine 5mg/ml plus 1ml of ketorolac 30mg/ml plus 0.5ml adrenaline 1mg/ml injected in medial and lateral retinaculum, medial and lateral collateral ligaments, quadriceps and patellar tendon, joint capsule, subcutaneous fat before closure.
Experimental: TKA with pain management by IV/oral analgesics.
Patients going TKA and getting a standard pain control regime of IV opioids when needed, IV ketorolac, and IV/oral paracetamol.
Related Therapeutic Areas
Sponsors
Leads: Damascus University