A Clinical Research on the Safety/Efficacy of Human Umbilical Cord Mesenchymal Stem Cells（19#iSCLife®-OA） Therapy for Patients With Osteoarthritis
The purpose of this study is verify the efficacy and safety of Human Umbilical Cord Mesenchymal Stem Cells (UC-MSC) therapy for patients with Osteoarthritis, and in addition, provide basis for exploring the treatment regimen of UC-MSC therapy in different degree of cartilage defect disease
• Diagnosis of Knee Osteoarthritis by Kellgren and Lawrence Grading Scale, classified with Grade 2-3
• Confirm with cartilage injury,articular cartilage part or full-thickness injury, by MR (Magnetic Resonance)
• Age \<70, no serious organ dysfunction
• Over 2 years knee pain or no very effective with conservative treatments
• Knee pain of VAS (visual analog scale score) is 4 or higher
• Normal hepatic and renal function, no history of gout, rheumatoid arthritis, and autoimmune diseases, etc.
• Understand and sign the consent form of this study