In-vivo Evaluation of Glenohumeral Joint Contact Patterns in Osteoarthritic Glenoids

Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Observational
SUMMARY

Shoulder osteoarthritis (OA) is a frequent problem in our aging population and is believed to occur in up to 20% of the population. Different types of glenoid morphology are associated with shoulder OA, depending on the amount and localization of the glenoid erosion as well as the amount and direction of Humeral Head Migration. Total shoulder arthroplasty (TSA) has been shown to relieve the pain and improve joint function of patients with OA. However, several complications such as component loosening and polyethylene damage has been reported and it has been revealed that 7.3% of glenoids may show signs of asymptomatic radiographic loosening annually after primary anatomic TSA. The mechanism of such fixation failure is still unclear. The main goal of this study is evaluating in-vivo glenohumeral contact patterns in patients with osteoarthritic glenoids before and after TSA, to unravel the high rate of glenoid component loosening.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

⁃ OA patients group

• Patients with glenohumeral osteoarthritis planned for anatomic shoulder arthroplasty in the University Hospitals Leuven, Belgium

• Complete patient informed consent

• Pain free at the time of EOS imaging

⁃ Healthy control group

• Healthy adult volunteers with no history of shoulder pain or trauma

• Confirmation of the physician, that subject's clinical evaluation and CT scan did not show any abnormalities

• Complete informed consent

Locations
Other Locations
Belgium
UZ Leuven
RECRUITING
Leuven
Contact Information
Primary
Filip Verhaegen
filip.verhaegen@uzleuven.be
+32 16 33 88 27
Backup
Philippe Debeer
philippe.debeer@uzleuven.be
+32 16 33 88 37
Time Frame
Start Date: 2021-11-03
Estimated Completion Date: 2026-07-01
Participants
Target number of participants: 52
Treatments
Shoulder osteoarthritis patients
Patients with glenohumeral osteoarthritis
Healthy control
Healthy adult volunteers with no history of shoulder pain or trauma
Related Therapeutic Areas
Sponsors
Leads: Universitaire Ziekenhuizen KU Leuven

This content was sourced from clinicaltrials.gov