• Subjects voluntarily particpate in this clinical study and sign the informed consent form.

• Male and female patients aged 18-75 years at the time of screening (both inclusive)

• Meet the diagnosis of active Ankylosing Spondylitis(AS), have a record of radiological evidence consistent with the Modified New York Classification Criteria for ankylosing spondylitis as revised in 1984 4. Diagnosis of active AS (active AS is defined as: BASDAI \>= 4, total back pain score \>=4, and BASDAI second question spinal pain score \>=4)