Metformin Treatment of Patients with Hand Osteoarthritis: a Randomised, Placebo-controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥18 years
• Hand OA according to the ACR criteria
• Average finger (2 to 5) pain ≥4 on a 0-10 numeric rating scale (NRS where 10 is worst pain) over the past 30 days
• Metformin naive
Locations
Other Locations
Denmark
The Parker Institute, Bispebjerg and Frederiksberg hospital
RECRUITING
Copenhagen
Contact Information
Primary
Kasper Staberg Madsen
kasper.staberg.madsen@regionh.dk
+4538164162
Time Frame
Start Date: 2024-06-03
Estimated Completion Date: 2026-04
Participants
Target number of participants: 150
Treatments
Experimental: Metformin
Placebo_comparator: Placebo
Related Therapeutic Areas
Sponsors
Leads: Marius Henriksen