Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis refractory to conservative treatment. The main questions it aims to answer are: * Does CT-guided genicular nerve ablation provide superior pain relief compared to fluoroscopic-guided genicular nerve ablation? * Is there a significant difference in functional improvement between the two techniques? Researchers will compare the outcomes between the CT-guided and fluoroscopic-guided groups to determine which method achieves better pain relief, functional enhancement, safety profile, and patient satisfaction. Participants will: * Undergo either CT-guided or fluoroscopic-guided genicular nerve ablation. * Attend scheduled follow-up visits to assess pain levels, knee function, and any adverse events. * Complete standardized questionnaires to provide feedback on pain relief, functional improvement, and overall satisfaction with the procedure.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 80
Healthy Volunteers: f
View:

• Adults aged 45 to 80 years.

• Diagnosed with knee osteoarthritis.

• Knee osteoarthritis refractory to conservative treatment.

• Able to provide informed consent.

• Agree to follow the study procedures and attend follow-up visits.

Locations
Other Locations
Egypt
Zagazig University, Faculty of Medicine
RECRUITING
Zagazig
Contact Information
Primary
Ahmed A Bessar, MD, PhD
Ahmedawadbessar@gmail.com
+201000089595
Time Frame
Start Date: 2024-09-29
Estimated Completion Date: 2025-05-30
Participants
Target number of participants: 60
Treatments
Experimental: CT-Guided Genicular Nerve Ablation
Participants in this arm will undergo genicular nerve ablation using computed tomography (CT) guidance. The procedure involves precise needle placement based on CT imaging to effectively target the genicular nerves responsible for transmitting pain signals from the knee.
Active_comparator: Fluoroscopic-Guided Genicular Nerve Ablation
Participants in this arm will receive genicular nerve ablation using fluoroscopic guidance. The procedure utilizes real-time fluoroscopy to guide needle placement for the ablation of the genicular nerves.
Related Therapeutic Areas
Sponsors
Leads: Zagazig University

This content was sourced from clinicaltrials.gov