Analisi Della Perdita di Forza e Potenza Muscolare e Del Degrado Del Controllo Motorio Per la Predizione Delle Cadute in Una Popolazione Affetta da Artrosi di Ginocchio

Status: Recruiting
Location: See location...
Intervention Type: Other, Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is: ● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population? Participants will undergo: * Muscle force assessment on a dynamometer * Muscle power assessment on a dynamometer and on isntrumented stairs * Home-based mobility monitoring * Full lower limb MRI acquisition * Gait assessment

Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Maximum Age: 80
Healthy Volunteers: f
View:

• Age between 65 and 80 years

• Kellgren score II e III

• No history of falls in the last 12 months

Locations
Other Locations
Italy
IRCCS Istituto Ortopedico Rizzoli
RECRUITING
Bologna
Contact Information
Primary
Lisa Berti, Professor
lisa.berti@ior.it
+390516366529
Backup
Massimiliano Baleani, Engineer
massimiliano.baleani@ior.it
+390516366865
Time Frame
Start Date: 2025-01-30
Estimated Completion Date: 2026-12-12
Participants
Target number of participants: 50
Treatments
Experimental: Knee Osteoarthritis
Elderly patients with knee osteoarthritis, without a history of falls (in the 12 months prior to enrollment).~All subjects will be followed up for 24 months, every 6 months. Muscle force and power assessments, plus a home-based mobility monitoring, will be performed at all visits. Full lower limb MRI and a gait assessment will be performed at first and last visit.
Related Therapeutic Areas
Sponsors
Leads: Istituto Ortopedico Rizzoli

This content was sourced from clinicaltrials.gov

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