Prospective, Randomized, Double-blind Clinical Trial to Investigate the Efficacy of Autologous Bone Marrow Aspirate Concentrate Post-Meniscectomy
The proposed research study aims to evaluate the effects of autologous bone marrow aspirate concentrate (BMAC) on the development and progression of osteoarthritis (OA) in patients undergoing meniscectomy. This prospective, randomized, double-blind clinical trial will compare patient-reported outcomes, specifically IKDC scores between patients who receive BMAC post-meniscectomy and those who receive a saline control injection. The study will also compare physical examination, MRI, radiographs, and synovial fluid analysis. Our hypothesis is that those who receive the autologous BMAC injection after the procedure will have better outcomes than those who do not.
• Subject is greater than 18 years old
• Written informed consent is obtained
• Subject is determined to have a symptomatic meniscal tear requiring a meniscectomy
• Meniscal pathology is confirmed through MRI and arthroscopically
• Subject agrees to all follow-up evaluations
• Osteoarthritis Kellen-Lawrence grade 1-3 on flexion PA and extension AP views