Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy: Effectiveness of 5 Nerve Protocols Versus 3 Nerve and 2 Nerve Protocols - A Prospective Randomized Controlled Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The main symptom of knee osteoarthritis, which occurs after damage to the joint cartilage with age, is pain, but this symptom often becomes chronic. Current conservative treatments have moderate effects on chronic knee pain and their use is limited due to the risk of side effects. In addition to pain, patients also experience other symptoms. As a result of the osteoarthritis process, prorioception in the knee is impaired with a decrease in mechanoreceptors, resulting in loss of balance and an increase in the risk of falling.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 75
Healthy Volunteers: f
View:

• Age between 30-75

• Chronic knee pain that lasts at least 6 months

• Radiographic confirmation of osteoarthritis: Presence of Grade 3 or 4 radiographic changes characterized by significant narrowing in the medial space of the tibiofemoral joint according to the Kellgren-Lawrence classification system

• Knee pain \>40 mm when performing one of the two movements that cause the most severe pain (sitting to standing or going up and down stairs) according to 100 mm VAS

⁃ 50% reduction in VAS with diagnostic genicular nerve block

Locations
Other Locations
Turkey
Ankara Etlik City Hospital, Physical Medicine and Rehabilitation
RECRUITING
Ankara
Contact Information
Primary
Bengu Turemenogullari
drbenguturemen@gmail.com
+905072848966
Time Frame
Start Date: 2025-04-15
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 66
Treatments
Active_comparator: Radiofrequency Ablation Targeting Two Genicular Nerves
2 nerve radiofrequency ablation: Superior Medial (SM) and Inferior Medial (IM) branches.~A group of patients will receive a single treatment session using the Radiofrequency Ablation method for 2 nerves, Superior Medial (SM) and Inferior Medial (IM).
Active_comparator: Radiofrequency Ablation Targeting Three Genicular Nerves
3 nerve radiofrequency ablation: Superior Medial (SM), Superıor Lateral (SL) and Inferior Medial (IM) branches.~A group of patients will receive a single treatment session using the Radiofrequency Ablation method for 3 nerves, Superior Medial (SM), Superior Lateral (SL) and Inferior Medial (IM).
Active_comparator: Radiofrequency Ablation Targeting Five Genicular Nerves
5 nerve radiofrequency ablation: Superior Medial (SM), Superıor Lateral (SL), Inferior Medial(IM), Rekurren Fibular Nerve (RFN) and İnfrapatellar Branch of Saphenous Nerve (IPBSN).~Another group of patients will receive a single treatment session with Radiofrequency Ablation for 5 nerves: Superior Medial (SM), Superior Lateral (SL), Inferior Medial (IM), Recurrent Fibular Nerve (RFN) and Infrapatellar Branch of Saphenous Nerve (IPBSN).
Related Therapeutic Areas
Sponsors
Leads: Bengu Turemenogullari

This content was sourced from clinicaltrials.gov