Ultrasonication-mediated Microbubbles Dressings Increase the Therapeutic Efficacy of Piroxicam Gel for Hand Arthritis: Assessments Using Conventional and Ultrafast Power Doppler Imaging
The goal of this clinical trial is to learn if ultrasonication-mediated microbubbles dressing works to treat hand arthritis in adults. It will also learn about the safety of ultrasonication-mediated microbubbles dressing. The main questions it aims to answer are: Does ultrasonication-mediated microbubbles dressing increase the therapeutic efficacy of piroxicam gel for hand arthritis? Researchers will compare ultrasonication-mediated microbubbles dressing + piroxicam gel to ultrasonication + piroxicam gel and piroxicam gel alone to see if ultrasonication-mediated microbubbles dressing works to treat hand arthritis. Participants will: Take ultrasonication-mediated microbubbles dressing (day 1,3,5) + piroxicam gel (day 2,4,6,7) , ultrasonication (day 1,3,5) + piroxicam gel (day 2.4.6.7), and piroxicam gel alone (day 1-7) for 1 week. Visit the clinic on day 1 and day 8 for checkups and tests Keep a diary of their symptoms
• Clinical diagnosis of hand arthritis
• Have at least three symptomatic joints over wrist, metacarpophalangeal joints, and interphalangeal joints