Programmed Intermittent Bolus for Infusion of Local Anesthetic During Continuous Interscalene Nerve Blockade for Total Shoulder Arthroplasty: a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A new infusion strategy named the 'programmed intermittent bolus' (PIB) technique delivers the hourly dose within minutes compared to the traditional infusion that delivers such dose over an hour. The PIB technique has demonstrated superior patient satisfaction and reduced local anesthetic consumption when utilized for pain control during labour and delivery. However, it is not known if the PIB technique gives any benefits during a continuous nerve block in other settings. The aim of this randomized controlled trial (RCT) is to elucidate if PIB is better than (traditional) continuous infusion for postoperative analgesia in patients receiving a continuous nerve block for total shoulder arthroplasty with respect to pain control.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult patients

• American Society of Anesthesiologists (ASA) Physical Status I to III

Locations
Other Locations
Canada
St. Joseph's Health Care London
RECRUITING
London
Contact Information
Primary
Bill Lin, FRCPC
cheng.lin@lhsc.on.ca
+15196466000
Time Frame
Start Date: 2022-01-01
Estimated Completion Date: 2024-12
Participants
Target number of participants: 110
Treatments
Experimental: Programmed Intermittent Bolus (PIB)
For the experimental group, patients will receive 5 mL of the study solution as a bolus every hour via a PIB-capable infusion pump.
Active_comparator: Continuous Infusion
The control (standard care) group will receive the study solution at a rate of 5mL/h continuously via the current infusion pump.
Related Therapeutic Areas
Sponsors
Leads: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

This content was sourced from clinicaltrials.gov