Novel Sensors and Artificial Intelligence for Detection of Acute Pulmonary Exacerbations in Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

The goal of this observational study is to learn about new sensors that measure changes in the body that happen during a chest infection, such as breathing rate and heart rate. This study will be with adults who have either cystic fibrosis or bronchiectasis who start treatment with intravenous antibiotics (usually for around 2 weeks). The main question it aims to answer is the change in sensor measure (such as heart rate) between the start and end of treatment for a chest infection. No follow up visits are required for this study.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• ≥ 18 years old

• Diagnosis of CF based on genetic testing and /or sweat chloride levels or CT confirmed diagnosis of non-CF bronchiectasis

• Under the care of Royal Papworth Hospital

• Starting IV antibiotics for treatment of APE as defined by the Hill Criteria ²

Locations
Other Locations
United Kingdom
Royal Papworth Hospital NHS Foundation Trust
RECRUITING
Cambridge
Contact Information
Primary
Lucy E Gale
lucy.gale1@nhs.net
+44 1223 638000
Backup
Victoria Hughes, PhD
victoria.hughes1@nhs.net
+44 1223 638000
Time Frame
Start Date: 2025-09-30
Estimated Completion Date: 2026-04-30
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Collaborators: University of Cambridge, Department of Health, United Kingdom, LifeArc, National Institute for Health Research, United Kingdom
Leads: Papworth Hospital NHS Foundation Trust

This content was sourced from clinicaltrials.gov