Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in People With Long COVID-19.

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This Randomized Controlled Trial (RCT) aims to assess the effectiveness and acceptability of the Unified Protocol (UP) in an online group format for the treatment of emotional disorders in adults. Participants will be 90 adults (45 in the control group and 45 in the experimental group) with diagnosis of long COVID and comorbid emotional disorders. Participants will be recruited at Hospital Royo Villanova from Zaragoza, Spain. In this study it will be explored whether the changes obtained after the intervention in emotional disorders and cognitive complaints are maintained over 12 months. Additionally, levels of chronic stress will be longitudinally evaluated in the experimental group through accumulated cortisol levels in hair, before and after the application of the UP.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Residing in Autonomous Community of Aragon (Spain).

• Being at least 18 years old.

• Understanding of Spanish.

• Being diagnosed with long COVID-19: documented SARS-CoV-2 infection and persistence of symptoms beyond 12 weeks after the acute infection.

• Symptoms of depression (ODSIS≥7) and/or anxiety (OASIS≥8).

• Meeting the criteria for an emotional disorder diagnosis.

• Having access to Internet.

• Signing the informed consent.

Locations
Other Locations
Spain
Hospital Royo Villanova
RECRUITING
Zaragoza
Hospital Royo Villanova
NOT_YET_RECRUITING
Zaragoza
Contact Information
Primary
Jorge Osma Jorge Osma, PhD
osma@unizar.es
+34 978645390
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 90
Treatments
Experimental: Unified Protocol Psychological Intervention
The 45 participants assigned to this condition will receive the Unified Protocol psychological intervention through 12 sessions. Weekly session will be conducted online (via Google Meet). Each sessions will last 2 hours.
Other: Control Group-Waiting list
The 45 participants assigned to this condition will remain as a control group on a waiting list for the 12 weeks of the program that participants in the experimental group receive.
Related Therapeutic Areas
Sponsors
Collaborators: Hospital Royo Villanova de Zaragoza
Leads: Instituto de Investigación Sanitaria Aragón

This content was sourced from clinicaltrials.gov

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