FMT for Alcohol Use Disorder in Cirrhotics: A Randomized Controlled Trial.
* Title FMT for Alcohol Use Disorder in cirrhotics: A Randomized Controlled Trial * The aim of the study is to study the efficacy of Fecal microbiota transplantation in patients with Alcohol liver disease over a 6 month duration without liver related side effects. The project will be conducted at ILBS over the period of 1 year. * The concept is to test the efficacy of FMT in alcohol related cirrhotics by its effect on achieving and maintaining abstinence and in reducing lapses and relapses. Thereby reducing the progression of alcoholic liver disease as continued ethanol consumption is an important predictor in increasing overall morbidity and mortality.
• All consecutive patients with alcohol related cirrhosis with serum bilirubin \<5mg/dl with an active alcohol consumption atleast within last 4 weeks aged between 18 -70yrs.
• Fulfilling DSM - 5 criteria for alcohol use disorder (Association, 2013).