Team Science to Identify & Intervene on Metabolism- & Alcohol-Associated Liver Disease

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Liver damage from alcohol intake and weight-related behaviors is preventable and treatable only through lifestyle changes. This mixed-methods randomized controlled trial compares standard and enhanced approaches to screening, brief intervention, and referral to treatment/prevention (SBIRT/P) to identify and intervene for metabolism- and alcohol-associated liver disease (MetALD). Our multidisciplinary team aims to show that integrating results of noninvasive liver screening with Fibroscan®, a painless ultrasound that measures stiffness and fat in the liver, can optimize our brief intervention. The study population is adults age 21+ who speak Spanish or English from underresourced communities with alcohol- and weight-related risks for MetALD.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Healthy Volunteers: f
View:

• Be at least 21 years of age.

• Exceed alcohol intake screening guidelines for MetALD.

• Have a Body Mass Index (BMI) \>=25 kg/m2.

• Be able to speak and read English or Spanish to provide written informed consent and understand written and oral instructions in English or Spanish.

Locations
United States
Rhode Island
Clinica Esperanza Hope Clinic
RECRUITING
Providence
Contact Information
Primary
Primary Researcher
liverhealth@brown.edu
401-863-6623
Time Frame
Start Date: 2025-04-25
Estimated Completion Date: 2025-07-31
Participants
Target number of participants: 40
Treatments
Active_comparator: Standard Intervention
Participants randomly assigned to this arm will receive psychotherapy utilizing manualized principles of motivational interviewing with standard health information.
Experimental: Enhanced Intervention
Participants randomly assigned to this arm will receive psychotherapy utilizing manualized principles of motivational interviewing that incorporates personalized feedback on self-reported alcohol intake and two scores from Fibroscan® liver imaging that indicate steatosis (liver fat) and fibrosis (liver scaring).
Sponsors
Leads: Brown University
Collaborators: National Institute of General Medical Sciences (NIGMS)

This content was sourced from clinicaltrials.gov

Similar Clinical Trials