Impact of Thermocoagulation During Invasive EEG Monitoring in Children With Focal Drug-resistant Epilepsies

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

When focal epilepsies become drug-resistant, it could be eligible for cortical surgical resection. Therefore, an invasive EEG monitoring with depth electrodes is often needed during presurgical evaluation. Some of these children can have access to thermocoagulation inside the ictal onset zone, at the end of the monitoring and before to remove the electrodes. These thermocoagulations can disorganize the epileptogenic network thanks to millimetric cortical lesions around the electrodes. The aim is to stop or at least, to reduce the seizure frequency for few weeks or months. This could be a benefit for the child, and also a confirmation of the ictal onset zone and guide the surgeon. This technique is currently used in adult population for years, but remains very rare in children.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 1
Maximum Age: 17
Healthy Volunteers: f
View:

• age 18 month to 17 years old

• focal drug-resistant epilepsy

• small size lesion (1 or 2 gyri) or cryptogenic epilepsy

• indication for EEG monitoring with depth electrodes during presurgical evaluation

Locations
Other Locations
France
Fondation Ophtalmologique Adolphe de Rothschild
RECRUITING
Paris
Contact Information
Primary
Laurence SALOMON, MD, PhD
lsalomon@for.paris
0033148036431
Time Frame
Start Date: 2015-12
Estimated Completion Date: 2024-06-11
Participants
Target number of participants: 100
Treatments
Experimental: Thermocoagulation
Related Therapeutic Areas
Sponsors
Leads: Fondation Ophtalmologique Adolphe de Rothschild

This content was sourced from clinicaltrials.gov