Exploring Long-COVID Impact on Cognition Through Digital Neuropsychological Assessment

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The persistence of the COVID-19 disease symptoms, such as extreme fatigue, shortness of breath, cardiovascular complications, depression and anxiety, pain, brain fog, loss of taste/smell, headaches as well as loss of memory has been evoked in many studies. This project aims at approaching the persistent symptomatology on cognition, more than 1 year after the infection. When we refer to cognition, we refer to everything associated with knowledge, that is, the accumulation of information we have acquired through learning or from our experience. We can define cognitive processes as the processes we use to incorporate new knowledge and make decisions based on it. Through these processes several cognitive functions intervene: perception, attention, memory, reasoning, language, learning, decision-making. All of these cognitive functions work together to integrate knowledge as a whole and create an interpretation of the world around us. Usually neuropsychological tests are used to evaluate cognitive problems, they consist in different exercises sometimes with words, figures to draw, images to remember, movement to repeat, numbers to link together etc. The DigiCog project here propose 1. to test and validate a very novel device, which uses the eyes movement during tasks to evaluate very quickly the cognitive functioning; 2. to study potential cognitive problems long-term after COVID-19; and 3. to explore how cognition could be preserved. Finally, this project will also help to bring the innovative device tested to the market, for accurately monitoring people with long COVID.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 25
Maximum Age: 65
Healthy Volunteers: t
View:

• Participants who have previously participated in the Predi-COVID study (Registration number NCT04380987), or who have experienced COVID-19 at least once before 2022.

• Participants who have signed the informed consent form

• Participants aged between 25 and 65 years old

Locations
Other Locations
Luxembourg
Luxembourg Institute of Health, LCTR
RECRUITING
Luxembourg
Contact Information
Primary
Magali PERQUIN, PhD
magali.perquin@lih.lu
(+352) 26970
Backup
Manon GANTENBEIN, PhD
manon.gantenbein@lih.lu
Time Frame
Start Date: 2023-04-15
Estimated Completion Date: 2025-09-30
Participants
Target number of participants: 300
Treatments
Other: DigiCog Intervention
Although DigiCog participants receive two interventions (the new digital device and the gold standard method), they are not randomized to different intervention groups. Instead, each participant serves as their own control, receiving both interventions sequentially. Therefore, the study has one arm.
Related Therapeutic Areas
Sponsors
Leads: Luxembourg Institute of Health
Collaborators: ViewMind

This content was sourced from clinicaltrials.gov