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Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patient undergoing surgery is exposed to many stressors: diachronic (gesture anticipation), synchronic (intraoperative aggression) and historical (subject's personality). Reducing the level of stress experienced is a factor for improving the quality of the surgical gesture and the simplicity of the follow-up. The previous methods used were intended to reduce the body's reactivity to aggressions through anaesthesia consultation and L-Tyrosine supplementation. Currently with the progression of outpatient surgery and the need for early rehabilitation, L-Tyrosine supplementation is suppressed to improve recovery. Some patients, however, have a high level of stress that may require anxiolysis when the ideal treatment does not exist (ineffective hydroxyzine, benzodiazepines having many side effects). The strategy of this work is to improve the body's ability to respond to stressors, by administering l-tyrosine with no impact on waking or returning home.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Membership of a social security scheme or equivalent

• At least 18 years of age

• Able to express consent

• Indication of unilateral or bilateral inguinal hernia cure

• General anaesthesia proposed and retained for inguinal hernia treatment regardless of surgical technique

Locations
Other Locations
Monaco
CHPG
RECRUITING
Monaco
Contact Information
Primary
Bertrand PRUNET, PU-PH
bertrand.prunet@chpg.mc
+377 97 98 98 19
Backup
Nicolas RIJO
nicolas.rijo@chpg.mc
+377 97 98 84 45
Time Frame
Start Date: 2023-11-14
Estimated Completion Date: 2026-05
Participants
Target number of participants: 150
Treatments
Experimental: L-Tyrosine
Placebo_comparator: Placebo
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire de Nice

This content was sourced from clinicaltrials.gov