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ROLL'YN-OMA : Etude Observationnelle de Cohorte Pour la Prise en Charge Des Patients Atteints de Pathologies Inflammatoires Chroniques traités Par Omlyclo®, un Omalizumab Biosimilaire

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY

ROLL'YN-OMA is a real-world study in patients receiving standard biologic therapies who have been in control and/or remission of their disease for at least 3 months and whose physician has independently decided, within the framework of a shared medical decision, to switch them to OMLYCLO®. The primary objective of this study is to evaluate the maintenance of this control and/or clinical remission 12 months after initiation of the biosimilar, and subsequently, patient satisfaction at 6 and 12 months.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Be an adult (aged 18 years or older at the time of inclusion) receiving specialist care and diagnosed with one of the following conditions: Severe asthma, Chronic Spontaneous Urticaria

• Have been treated for at least 6 months prior to inclusion with the reference omalizumab for the relevant condition (Severe asthma or Chronic Spontaneous Urticaria).

• Have been stable for at least 3 months according to the prescribing physician, with the disease controlled or in clinical remission based on the disease-specific activity score: Severe asthma: ≤ 1 course of oral corticosteroids per year related to disease worsening, without hospitalization, and ACQ \< 1.5 and FEV1 ≥ 80% of the patient's most recent values/ Chronic Spontaneous Urticaria : UCT ≥ 12

• For whom the specialist physician has decided to switch to OMLYCLO® (biosimilar developed and marketed by Celltrion) on the day of patient inclusion (shared medical decision independent of the study).

• Be able to start treatment within a maximum of 60 days following inclusion.

• Have an email address.

• Have a mobile phone number.

• Be able to understand and complete questionnaires in French.

• Not object to participating in the study.

• Be affiliated with a French Social Security scheme or be a beneficiary of such a scheme

Locations
Other Locations
France
CHU Montpellier
RECRUITING
Montpellier
Contact Information
Primary
Salim BENKHALIFA, MD
rollyn-oma@sanoia.com
+33 1 71 25 27 00
Time Frame
Start Date: 2025-10-02
Estimated Completion Date: 2028-09
Participants
Target number of participants: 225
Treatments
CSU group
Switch from omalizumab originator in patients with CSU
Allergic asthma group
Switch from omalizumab originator in patients with allergic asthma
Related Therapeutic Areas
Sponsors
Leads: Celltrion HealthCare France

This content was sourced from clinicaltrials.gov