Retinal Imaging Study of Children That Might be at Risk of Having Retinal Hemorrhages

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This is a clinical trial in which we will learn about the retinal findings in three clinical groups of children, who might be at risk of having retinal hemorrhages (RH). The aim of the study is to explore the occurrence of moderate to severe retinal hemorrhages in critically ill children, children with intracranial hemorrhages, hydrocephalus or signs of elevated intracranial pressure and in children with benign enlargement of subarachnoid spaces (BESS). 1. Are RHs associated with BESS? 2. What is the prevalence, distribution and extent of RHs in critically ill children? 3. What is the prevalence, distribution and extent of RHs in children with traumatic brain injury? 4. Does the prevalence, distribution and extent of RHs differ in children with witnessed traumatic brain injury from children with traumatic brain injury of unknown origin? 5. To what extent do the causes of RHs affect visual acuity, initially and during recovery? A retinal ophthalmoscopy through dilated pupils will be conducted and a fundus photograph will be taken by a handheld, non-touch camera.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 28 days
Maximum Age: 14
Healthy Volunteers: t
View:

• Infants ≤ 18 months of age, who undergo neuroradiological examinations of the brain on the indication increased head circumference

• Children \< 15 years of age, cared for at the ICU, with neurological symptoms, that require neuroradiological examination of the brain

• Children \< 5 years of age, who undergo emergency neuroradiological examinations of the head at the hospitals

Locations
Other Locations
Sweden
Kerstin Margareta Hellgren
RECRUITING
Stockholm
Contact Information
Primary
Hannamaria Öhnell, MD, PhD
hanna_maria.ohnell@med.lu.se
+4640-332781
Backup
Gunilla Magnusson, MD, PhD
gunilla.magnusson@vgregion.se
+4631- 343 32 56
Time Frame
Start Date: 2023-02-08
Estimated Completion Date: 2026-02-08
Participants
Target number of participants: 1500
Treatments
Accelerating head growth in infancy
Infants \<=18 months of age referred to head ultrasound because of accelerating head growth
Children at ICU with neurological symptoms that require brain MRI or CT
Children \< 15 years of age who are cared for at ICU becaus of neurological symptoms that require brain MRI or CT scans
Children entering the emergency department with the need of acute brain CT
Children \< 2 years of age that enter the emergency department because of brainthreatening conditions that require acute brain CT scans
Sponsors
Leads: Region Stockholm

This content was sourced from clinicaltrials.gov