Shunt-dependency After Aneurysmal Subarachnoid Haemorrhage - the Role of Early Hyperglycaemia in Cerebro-spinal Fluid and Blood

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The goal of this study is to confirm the association of early increased glucose levels in cerebro-spinal fluid (CSF) and ventriculo-peritoneal-shunt (VPS)-dependency also evaluating the influence of blood glucose on VPS dependency in patients suffering from an aneurysmal subarachnoid haemorrhage (aSAH). The main questions we aim to answer are: * Is there an association of glucose levels on VPS dependency in patients requiring extra-ventricular-drain (EVD) placement for aSAH? * In addition, if there is, what is the influence the course of glucose levels has on VPS dependency? Glucose levels in CSF and serum will be measured on admission, or in case of CSF, upon EVD placement. Glucose in CSF will then be measured every day until EVD removal together with serum glucose. Follow-up will be conducted in person after 3 and 6 months.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 18 years old and older

• Hospital admission due to an aneurysmal subarachnoid haemorrhage (radiological confirmation needed)

Locations
Other Locations
Switzerland
Cantonal Hospital Aarau
RECRUITING
Aarau
University Hospital Basel
RECRUITING
Basel
Cantonal Hospital St Gallen
RECRUITING
Sankt Gallen
Contact Information
Primary
Isabel Hostettler, MD PhD
isabel.hostettler@kssg.ch
+41 71 494 97 40
Backup
Lauren Wiebe, BSN MSc
lauren.wiebe@kssg.ch
Time Frame
Start Date: 2024-03-26
Estimated Completion Date: 2027-09
Participants
Target number of participants: 160
Treatments
aSAH Patients
Patients with an acute ruptured intracranial aneurysm.
Related Therapeutic Areas
Sponsors
Leads: Isabel Hostettler
Collaborators: Kantonsspital Aarau, University Hospital, Basel, Switzerland

This content was sourced from clinicaltrials.gov