Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The objective of this proposal is to study circulating and echocardiographic markers of pulmonary vascular and right ventricular remodeling in patients with a WHO-2 diagnosis of pulmonary hypertension after mitral valve procedures. The investigators are proposing the study will be impactful for the early detection and prediction and of residual pulmonary hypertension (PH) that would otherwise be undetected and fatal with no curative treatment.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:
• \>= 18 years/old
Locations
United States
Alabama
The University of Alabama at Birmingham
RECRUITING
Birmingham
Contact Information
Primary
Kera Marshall
keramarshall@uabmc.edu
205-934-4042
Backup
LaShun Horn, MS
llhorn@uabmc.edu
205-996-2606
Time Frame
Start Date: 2021-12-21
Estimated Completion Date: 2026-01-20
Participants
Target number of participants: 120
Treatments
Patients with moderate mitral valve disease, undergoing interventions
Patients with established WHO-2 diagnosis of PH undergoing open and interventional mitral valve procedures.
Patients undergoing mitral valve interventions without pulmonary hypertension
Patients with no PH undergoing open and interventional mitral valve procedures. This group will serve as a control.
Patients with precapillary pulmonary hypertension scheduled for right heart catheterization
Patients with established diagnosis of WHO-1-4 groups of PH undergoing right heart catheterization. This group will serve as a control.
Related Therapeutic Areas
Sponsors
Leads: University of Alabama at Birmingham