Scaling Out and Scaling Up the Systems Analysis and Improvement Approach to Optimize the Hypertension Diagnosis and Care Cascade for HIV-infected Individuals

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Undiagnosed and untreated hypertension is a main driver of cardiovascular disease, affecting disproportionately low and middle-income countries, where guidelines to screen and manage hypertension are poorly used. More than 13% of Mozambique adults are infected with HIV, and over 900,000 are on anti-retroviral therapy. HIV clinics are the only services within primary care providing continued care, and can be used to standardize and scale the hypertension care cascade. Hypertension affects 40% of Mozambican adults, and thus HIV and HTN often coexist in the same person. The investigators propose to use low-cost tools that improve service performance, promote routine hypertension diagnosis and management, and ameliorate flow through the hypertension cascade, thus improving patients outcomes. Building on a current project some districts of two provinces of central Mozambique, the investigators will establish scientific evidence on the effectiveness of a tool that uses cycles of evaluation and improvement of health system, to address the hypertension care cascade in HIV-infected people. The investigators will strengthen the framework currently in use (based on nurses) setting a novel modality delivered by district health supervisors, and will expand the geographic study area by adding 6 districts of one additional province in southern Mozambique (Maputo Province), to create a foundation for national scale-up. The Project planning phase (two years) will develop a multi-sectoral partnership of key stakeholders, establish national technical working groups with the participation of the provinces, and identify key facilitators and barriers that could affect uptake of the results, integration of high blood pressure and HIV services, scale-up to the entire country, and sustainability of the tested framework. Additionally, the investigators will i) conduct a six-months pilot study to assess feasibility and acceptability of the district supervisor-led intervention in one primary care facility; and, ii) redesign tools and standard operating procedures, as necessary. During the implementation phase (last three years) the investigators will deploy the district-based dissemination and implementation randomized trial in 18 health facilities - using an intervention that involves assessment, effectiveness evaluation, promotion of local uptake, implementation and maintenance - and determine the costs of the hypertension care cascade optimization, by estimating the total incremental costs.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Primary care facility with ongoing cohort of ART patients (minimum 800 patients)

Locations
Other Locations
Mozambique
Centro de Saude da Ponta do Ouro
RECRUITING
Bela Vista
Centro de Saude de Matutuine
RECRUITING
Bela Vista
Centro de Saude de Salamanga
RECRUITING
Bela Vista
Centro de Saúde de Chichuco
RECRUITING
Magude
Centro de Saúde de Magude
RECRUITING
Magude
Centro de Saúde de Motaze
RECRUITING
Magude
Contact Information
Primary
Ana OH Mocumbi, MD PhD
amocumbi@gmail.com
00258823294990
Backup
Sarah Gimbel, PhD
sgimbel@uw.edu
+1(206) 2914223
Time Frame
Start Date: 2023-02-14
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 18
Treatments
Experimental: intervention health facilities
Health facilities implement the optimization of the cascade under research team support and continuous supervision.
No_intervention: Control
Health facilities prior to intensive phase receive standard supervision without research team support
Related Therapeutic Areas
Sponsors
Collaborators: University of Washington, Instituto Nacional de Saúde, Mozambique, Mozambique Institute for Health Education and Research, National Heart, Lung, and Blood Institute (NHLBI)
Leads: Eduardo Mondlane University

This content was sourced from clinicaltrials.gov