Effects of AM vs. PM Exercise Training on Blood Pressure and Vascular Health in Postmenopausal Females With Hypertension

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown to be more effective than morning medication routines. Little information is available about the effectiveness of chronotherapy combined with exercise (i.e., planned physical activity) interventions in older adults with hypertension. The purpose of this study is to examine how exercise training performed in the morning and early evening affects blood pressure and other measures of blood vessel health in postmenopausal females with hypertension.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 55
Maximum Age: 80
Healthy Volunteers: f
View:

• Systolic BP equal to or greater than 130 mmHg without BP medication or greater than 120 mmHg with medication and diastolic blood pressure equal to and greater than 80 mmHg

• 55-80 years old

• Post-menopausal female

• Able to walk without assistance

Locations
United States
Michigan
Michigan State University
RECRUITING
East Lansing
Contact Information
Primary
Jill Slade, PhD
jslade@msu.edu
5178843351
Backup
Katharine Currie, PhD
curriek4@msu.edu
517-432-4073
Time Frame
Start Date: 2024-06-11
Estimated Completion Date: 2027-07-01
Participants
Target number of participants: 79
Treatments
Experimental: Morning (AM)
Exercise starting before 10:01 AM
Experimental: Evening (PM)
Exercise starting after 3:59 PM
Related Therapeutic Areas
Sponsors
Leads: Michigan State University
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)

This content was sourced from clinicaltrials.gov