Examining the Circadian Timing Effects of the Hypotensive Response to Exercise

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to learn how exercise timing affects blood pressure in adults with elevated or high blood pressure. Exercise can influence the body's natural 24-hour rhythms, including blood pressure patterns. A single exercise session can lower blood pressure for up to 24 hours, but it is not fully understood how the time-of-day for exercise affects this response. The main question this study aims to answer is: • When the same participant exercises at different times of day (morning, afternoon, or evening), how does this affect the participant's blood pressure over the next 24 hours? Participants will: * Undergo an in-lab assessment of individual biological rhythm that will indicate the clock-time for an individual's biological night * Complete 3 supervised treadmill exercise sessions * 1 in the biological morning (biological night + 10 hours) * 1 in the biological afternoon (biological night + 15 hours) * 1 in the biological evening (biological night + 20 hours) * Complete a 24-hour blood pressure assessment before and after each exercise session

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 39
Healthy Volunteers: f
View:

• 18-39 Years old

• Resting blood pressure greater than or equal to 120/80 mmHg or less than 140/90 mmHg

Locations
United States
Delaware
University of Delaware
RECRUITING
Newark
Contact Information
Primary
Freda Patterson, PhD
fredap@udel.edu
302-831-6588
Backup
Thomas Keiser
tkeiser@udel.edu
302-831-6588
Time Frame
Start Date: 2025-07-22
Estimated Completion Date: 2026-09
Participants
Target number of participants: 30
Treatments
Experimental: Morning
Exercise 10 hours after dim-light melatonin onset
Experimental: Afternoon
Exercise 15 hours after dim-light melatonin onset
Experimental: Evening
Exercise 20 hours after dim-light melatonin onset
Sponsors
Leads: Freda Patterson

This content was sourced from clinicaltrials.gov