MIND Foods and Aerobic Training in Black Adults With HTN: An ADRD Prevention Pilot RCT
The goal of this randomized controlled trial is to determine the impact of Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training on cognition in Black adults with high systolic blood pressure. Researchers will compare Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) versus Enhanced Usual Care (EUC) to evaluate the effects on cognition. Participants will complete cognitive and cardiovascular assessments, 24-hr blood pressure monitoring, standard blood pressure measurements, weight, fingerstick for HbA1c point-of-care testing, and questionnaires. Participants may also choose to participate in an optional blood draw for DNA Repair Capacity testing as a modifiable risk factor for aging-associated diseases.
• Fluent in English
• Marion County resident
• 35-75 years
• Self-identified non-Hispanic and Black/African-American/biracial including African-American
• Systolic BP of ≥140 in prior 12 months from a primary care visit
• Ability to see and read street signs (self report)
• Stable housing with independent access to kitchen, including functional stove or hotplate, oven, refrigerator, and freezer (self report)
• Activity independence per functional activities questionnaire (FAQ; \<3 responses of Require Assistance and 0 responses of Dependent)
• Normal cognition per six-item screener (SIS; score of ≥ 5)
⁃ Less than 20min on usual day of moderate or vigorous physical activity
⁃ Able to exercise safely per abbreviated Exercise Assessment for You (EASY) or primary care provider clearance
⁃ Mean systolic BP of ≥130 from 3 standard BP measurements taken by research staff following standardized wait periods.