Diagnosing and Monitoring Portal Hypertension Non-invasively Using Spleen Stiffness Measurement in Patients With Advanced Chronic Liver Disease: a Prospective Cohort Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The goal of this observational study is to assess non-invasive tools' efficacy in predicting portal hypertension-related complications in individuals with advanced chronic liver disease. The main question it aims to answer are: \- what are the cut-off values for non-invasive tests (NITs) (including LSM, SSM) that predict the presence and occurrence of hepatic decompensation in individuals with advanced chronic liver disease? Participants will undergo regular study visits involving non-invasive tests (LSM, SSM) and assessments to monitor hepatic decompensation over the study period.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age above 18years old
• Advanced chronic liver disease (defined as LSM ≥ 10kPa)
• Ability to provide informed consent
Locations
Other Locations
Canada
McGill University Health Centre
RECRUITING
Montreal
Contact Information
Primary
Amine Benmassaoud, MD
amine.benmassaoud@mcgill.ca
514-934-1934
Backup
Olivia Geraci, BSc
olivia.geraci@muhc.mcgill.ca
514-934-1934
Time Frame
Start Date: 2024-01-10
Estimated Completion Date: 2028-12
Participants
Target number of participants: 200
Related Therapeutic Areas
Sponsors
Leads: McGill University Health Centre/Research Institute of the McGill University Health Centre