Acute and Chronic Effects of Resistance Training Intensity on Cardiovascular Parameters of Postmenopausal Women With Systemic Arterial Hypertension

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to understand about the effects of resistance training (RT) intensity on cardiovascular parameters in postmenopausal women with systemic arterial hypertension (SAH). The main research questions are: * Does the intensity of RT impact blood pressure (BP) in postmenopausal women with SAH? * How does RT intensity affect heart rate (HR) and their variability (HRV), endothelial function (EF), and nitric oxide (NO) biomarker synthesis in this population? * What are the effects of RT intensity on affectivity and rate of perceived exertion (RPE)? Researchers will compare two different intensities of RT (60% of the load for 1 repetition maximum \[1RM\] and 80% of 1RM) to determine their effects on the mentioned cardiovascular and perceptual parameters. Participants will: In the acute experiment: * Perform the same RT session in a crossover design, training with 60% of 1RM in one condition and 80% of 1RM in another condition * Have BP, HR, and HRV measured before, immediately after, and for one hour post-session * Report affectivity before each session and at the end, along with RPE In the chronic experiment: * Be randomized into two groups: one training with 60% of 1RM and the other with 80% of 1RM * Undergo a 10-week intervention period with evaluations before, during, and after the intervention * Have BP, HR, affective responses, and RPE measured at multiple time points * Have EF, HRV, and salivary concentrations of NO biomarkers assessed before and after the intervention

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 50
Maximum Age: 65
Healthy Volunteers: f
View:

• Women with 50 to 65 old years;

• Postmenopausal diagnosis (amenorrhea for 12 months or more);

• Previous diagnosis of hypertension and treat with medications;

• Physically inactive.

Locations
Other Locations
Brazil
Laboratório de Fisiologia do Exercício e Metabolismo
RECRUITING
Ribeirão Preto
Contact Information
Primary
Leonardo S Gonçalves
leonardo.edfisica@usp.br
16981806105
Time Frame
Start Date: 2024-07-23
Estimated Completion Date: 2025-09
Participants
Target number of participants: 24
Treatments
Active_comparator: 80% of 1 repetition maximum
The recent guideliness suggest a resistance training intensity for this population between 50 and 80% of 1 repetition maximum (1RM), i.e, this group will training in accordance with the recommendations.~These group will be training with 80% 1RM, performining 8-10 repetitions per set.
Active_comparator: 60% of 1 repetition maximum
The recent guideliness suggest a resistance training intensity for this population between 50 and 80% of 1 repetition maximum (1RM), i.e, this group will training in accordance with the recommendations.~These group will be training with 60% 1RM, performining 18-20 repetitions per set.
Related Therapeutic Areas
Sponsors
Leads: University of Sao Paulo

This content was sourced from clinicaltrials.gov