Is There an Association Between Quadriceps Strength and Different Markers of Fragility in Patients With Cirrhosis?
Physical frailty and malnutrition are important factors in morbidity and mortality in patients with cirrhosis. No study has assessed the validity of Liver Frailty Index (LFI) against reference measures such as maximal lower limb strength. Main objective: To assess the association between LFI score and isometric maximal lower limb strength (quadriceps) in patients with cirrhosis.
⁃ SUBJECT :
• with a diagnosis of liver cirrhosis (regardless of cirrhosis stage and etiology)
• under the care of a physician practising in the University Hospital Estaing in Clermont-Ferrand
• affiliated to the french social security system
• male subjects aged 52 to 62
• female subjects aged 42 to 60
• BMI between 20 and 30 kg/m2
• no musculoskeletal problems limiting physical activity
• level of physical activity \< 3 hours per week
• affiliated to the french social security system