Efficacy of Electroacupuncture Combined With Pregabalin in the Treatment of Trigeminal Herpetic Neuralgia: a Multicenter Randomized Controlled Trial Study Protocol
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Trigeminal herpetic neuralgia is a common type of Zoster-associated Pain (ZAP), which troubles individuals in all ages and burdens society all over the world. Eleactroaupuncture (EA) is increasingly used in the treatment of ZAP due to its advantages such as low price, high safety, no adverse reactions, and high patient acceptance. Therefore, it is necessary to conduct randomized controlled trials to evaluate the effectiveness and safety of EA on ZAP and whether EA can be used as a substitute for pregabalin.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:
• meet the aforementioned diagnostic criteria for trigeminal ZAP, with a disease duration of 1 to 3 months;
• have a visual analog scale (VAS) score of 4 points ≤ VAS ≤ 7 points;
• be between 18 and 85 years old, regardless of gender;
• have clear consciousness, the ability to distinguish pain, and complete basic communication;
• voluntarily participate in the study, sign a written informed consent form, and fully understand the plan.
Locations
Other Locations
China
The Hangzhou Third People's Hospital
RECRUITING
Hangzhou
Contact Information
Primary
Pin Lin
yjlp1@163.com
1358876268686
Backup
Chengcheng Kong
njmukcc@163.com
8613868078286
Time Frame
Start Date:2024-02-07
Estimated Completion Date:2025-12-20
Participants
Target number of participants:102
Treatments
Active_comparator: Medication Group
Participants in the medication group would take 150-mg pregabalin capsules orally twice daily (total daily dose, 300 mg) for 4 weeks. The follow-up period is 3 months.
Experimental: EA Group
The subjects in this group will receive 3 times per week, and 4 weeks of continuous intervention for a total of 12 times. The follow-up period is 3 months.
Experimental: EA+Medication Group
The subjects in this group will receive 3 times per week, and 4 weeks of continuous intervention for a total of 12 times. The intervention including electroacupuncture(EA) treatment and combined with pregabalin (0.15g each time, twice daily). The follow-up period is 3 months.