NeuralgiaSymptoms, Doctors, Treatments, Advances & More
Learn About Neuralgia
Neuralgia is a sharp, shocking pain that follows the path of a nerve and is due to irritation or damage to the nerve.
Common neuralgias include:
- Postherpetic neuralgia (pain that continues after a bout of shingles)
- Trigeminal neuralgia (stabbing or electric-shock-like pain in parts of the face)
- Alcoholic neuropathy
- Peripheral neuropathy
Nerve pain; Painful neuropathy; Neuropathic pain
Causes of neuralgia include:
- Chemical irritation
- Chronic kidney disease
- Diabetes
- Infections, such as herpes zoster (shingles), HIV/AIDS, Lyme disease, and syphilis
- Chemotherapy medicines such as cisplatin, paclitaxel, or vincristine
- Pressure on nerves by nearby bones, ligaments, blood vessels, or tumors
- Trauma (including surgery)
- Underlying nervous system disorder (such as multiple sclerosis)
In many cases, the cause is unknown.
Postherpetic neuralgia and trigeminal neuralgia are the two most common forms of neuralgia. A related but less common neuralgia affects the glossopharyngeal nerve, which provides feeling to the throat.
Neuralgia is more common in older people, but it may occur at any age.
Symptoms may include any of the following:
- Increased sensitivity of the skin along the path of the damaged nerve, so that any touch or pressure is felt as pain
- Pain along the path of the nerve that is sharp or stabbing, in the same location each episode, comes and goes (intermittent) or is constant and burning, and may get worse when the area is moved
- Weakness or complete paralysis of muscles supplied by the same nerve
The treatment depends on the cause, location, and severity of the pain.
Medicines to control pain may include:
- Antidepressants
- Antiseizure medicines
- Over-the-counter or prescription pain medicines
- Pain medicines in the form of skin patches or creams
Other treatments may include:
- Shots with pain-relieving (anesthetic) medicines
- Nerve blocks
- Physical therapy (for some types of neuralgia, especially postherpetic neuralgia)
- Procedures to reduce feeling in the nerve (such as nerve ablation using radiofrequency, heat, balloon compression, or injection of chemicals)
- Surgery to take pressure off a nerve
- Alternative therapy, such as acupuncture or biofeedback
Procedures may not improve symptoms and can cause loss of feeling or abnormal sensations.
When other treatments fail, providers may try nerve or spinal cord stimulation. In rare cases, a procedure called motor cortex stimulation (MCS) is tried. An electrode is placed over part of a nerve, spinal cord, or brain and is hooked to a pulse generator under the skin. This changes how your nerves signal and it may reduce pain.
Albany Medical Center
Charles Argoff is a Pain Medicine provider practicing medicine in Albany, New York. Dr. Argoff is rated as an Elite provider by MediFind in the treatment of Neuralgia. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Chronic Pain, Neuralgia, Complex Regional Pain Syndrome, and Fibromyalgia. Dr. Argoff is currently accepting new patients.
Nanna Finnerup practices practicing medicine in Aarhus N, Denmark. Ms. Finnerup is rated as an Elite expert by MediFind in the treatment of Neuralgia. She is also highly rated in 10 other conditions, according to our data. Her clinical expertise encompasses Neuralgia, Acute Pain, Diabetic Neuropathy, Chronic Pain, and Mastectomy.
Madison Surgery Center Anesthesiology Department
Alaa Abd-Elsayed is an Anesthesiologist and a Pain Medicine provider practicing medicine in Madison, Wisconsin. Dr. Abd-Elsayed is rated as an Elite provider by MediFind in the treatment of Neuralgia. He is also highly rated in 13 other conditions, according to our data. His clinical expertise encompasses Neuralgia, Femoral Nerve Dysfunction, Chronic Pain, Tenotomy, and Knee Replacement. Dr. Abd-Elsayed is board certified in Anesthesiology and Pain Medicine. Dr. Abd-Elsayed is currently accepting new patients.
Most neuralgias are not life threatening and are not signs of other life-threatening disorders. For severe pain that does not improve, see a pain specialist so that you can explore all treatment options.
Most neuralgias respond to treatment. Attacks of pain usually come and go. But, attacks may become more frequent in some people as they get older.
Sometimes, the condition may improve on its own or disappear with time, even when the cause is not found.
Complications may include:
- Problems from surgery
- Disability caused by pain
- Side effects of medicines used to control pain
Contact your provider if:
- You develop shingles
- You have symptoms of neuralgia, especially if over-the-counter pain medicines do not relieve your pain
- You have severe pain (see a pain specialist)
Strict control of blood sugar may prevent nerve damage in people with diabetes. The herpes zoster vaccine significantly reduces the risk of developing shingles and postherpetic neuralgia. Antiviral medicines, if provided early, may prevent neuralgia after an acute episode of shingles.
Summary: This randomized controlled trial investigates whether adding Pain Neuroscience Education (PNE) to standard pre-operative physiotherapy improves outcomes after lumbar laminectomy. Chronic low back pain often involves central sensitization, where the nervous system continues amplifying pain signals even after the structural problem is surgically corrected, contributing to persistent neuropathic pain...
Summary: Postherpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ) and represents a major clinical challenge due to its chronicity and impact on quality of life. Current treatments for acute HZ pain have limited efficacy in preventing PHN, highlighting the need for effective preventive strategies targeting early pathophysiological mechanisms. Venlafaxine as a plausible and clinical...
Published Date: May 04, 2026
Published By: Joseph V. Campellone, MD, Professor of Neurology, Cooper-Inspira Neuroscience, Cooper Medical School of Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Cohen SP. Pain. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 26.
Katirji B. Disorders of peripheral nerves. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 106.
Smith AG, Shy ME. Peripheral neuropathies. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 388.