NeuralgiaSymptoms, Doctors, Treatments, Advances & More
Learn About Neuralgia
Neuralgia is a sharp, shocking pain that follows the path of a nerve and is due to irritation or damage to the nerve.
Common neuralgias include:
- Postherpetic neuralgia (pain that continues after a bout of shingles)
- Trigeminal neuralgia (stabbing or electric-shock-like pain in parts of the face)
- Alcoholic neuropathy
- Peripheral neuropathy
Nerve pain; Painful neuropathy; Neuropathic pain
Causes of neuralgia include:
- Chemical irritation
- Chronic kidney disease
- Diabetes
- Infections, such as herpes zoster (shingles), HIV/AIDS, Lyme disease, and syphilis
- Chemotherapy medicines such as cisplatin, paclitaxel, or vincristine
- Porphyria (blood disorder)
- Pressure on nerves by nearby bones, ligaments, blood vessels, or tumors
- Trauma (including surgery)
- Underlying nervous system disorder (such as multiple sclerosis)
In many cases, the cause is unknown.
Postherpetic neuralgia and trigeminal neuralgia are the two most common forms of neuralgia. A related but less common neuralgia affects the glossopharyngeal nerve, which provides feeling to the throat.
Neuralgia is more common in older people, but it may occur at any age.
Symptoms may include any of the following:
- Increased sensitivity of the skin along the path of the damaged nerve, so that any touch or pressure is felt as pain
- Pain along the path of the nerve that is sharp or stabbing, in the same location each episode, comes and goes (intermittent) or is constant and burning, and may get worse when the area is moved
- Weakness or complete paralysis of muscles supplied by the same nerve
Treatment depends on the cause, location, and severity of the pain.
Medicines to control pain may include:
- Antidepressants
- Antiseizure medicines
- Over-the-counter or prescription pain medicines
- Pain medicines in the form of skin patches or creams
Other treatments may include:
- Shots with pain-relieving (anesthetic) medicines
- Nerve blocks
- Physical therapy (for some types of neuralgia, especially postherpetic neuralgia)
- Procedures to reduce feeling in the nerve (such as nerve ablation using radiofrequency, heat, balloon compression, or injection of chemicals)
- Surgery to take pressure off a nerve
- Alternative therapy, such as acupuncture or biofeedback
Procedures may not improve symptoms and can cause loss of feeling or abnormal sensations.
When other treatments fail, providers may try nerve or spinal cord stimulation. In rare cases, a procedure called motor cortex stimulation (MCS) is tried. An electrode is placed over part of a nerve, spinal cord, or brain and is hooked to a pulse generator under the skin. This changes how your nerves signal and it may reduce pain.
BIDMC Department Of Neurology
Roy Freeman is a Neurologist practicing medicine in Boston, Massachusetts. Dr. Freeman is rated as an Elite provider by MediFind in the treatment of Neuralgia. He is also highly rated in 19 other conditions, according to our data. His clinical expertise encompasses Orthostatic Hypotension, Familial Dysautonomia, Low Blood Pressure, and Multiple System Atrophy. Dr. Freeman is board certified in American Board Of Psychiatry And Neurology.
Nanna Finnerup practices practicing medicine in Aarhus N, Denmark. Ms. Finnerup is rated as an Elite expert by MediFind in the treatment of Neuralgia. She is also highly rated in 10 other conditions, according to our data. Her clinical expertise encompasses Neuralgia, Acute Pain, Diabetic Neuropathy, Chronic Pain, and Mastectomy.
Johns Hopkins Hospital
Srinivasa Raja is an Anesthesiologist practicing medicine in Baltimore, Maryland. Dr. Raja is rated as an Elite provider by MediFind in the treatment of Neuralgia. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Neuralgia, Chronic Pain, Acute Pain, and Complex Regional Pain Syndrome.
Most neuralgias are not life threatening and are not signs of other life-threatening disorders. For severe pain that does not improve, see a pain specialist so that you can explore all treatment options.
Most neuralgias respond to treatment. Attacks of pain usually come and go. But, attacks may become more frequent in some people as they get older.
Sometimes, the condition may improve on its own or disappear with time, even when the cause is not found.
Complications may include:
- Problems from surgery
- Disability caused by pain
- Side effects of medicines used to control pain
Contact your provider if:
- You develop shingles
- You have symptoms of neuralgia, especially if over-the-counter pain medicines do not relieve your pain
- You have severe pain (see a pain specialist)
Strict control of blood sugar may prevent nerve damage in people with diabetes. In the case of shingles, antiviral medicines and the herpes zoster virus vaccine may prevent neuralgia.
Summary: Varicella-zoster virus (VZV) is one of the eight herpesviruses that infect humans by manifesting as varicella. After primary infection VZV remains latent for life. In 30% of individuals the virus reactivates causing a secondary infection, herpes zoster (HZ). The most common complication of HZ is post-herpetic neuralgia (PHN) and, in severe cases, disseminated infection and death. The incidence of ...
Summary: The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department. The main question it aims to answer is: Is a transgluteal sciatic nerve block better than standard of care in improving pain in ER patients with sciatic back pain? If there is a comparison group: Researchers will co...
Published Date: June 13, 2024
Published By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Cohen SP. Pain. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 388.
Katirji B. Disorders of peripheral nerves. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 106.
Smith AG, Shy ME. Peripheral neuropathies. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 388.