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Amputations in Childhood and Neuropathic Pain

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood. The study focuses on two types of neuropathic pain: phantom limb pain and residual limb pain. It also evaluates quality of life and functional autonomy in this population and explores potential associations between neuropathic pain, autonomy, quality of life, and age at amputation. Using a mixed retrospective and prospective design, data are collected from medical records and standardized questionnaires administered during routine follow-up visits at a specialized pediatric limb anomaly center. The study seeks to improve understanding of neuropathic pain after pediatric amputation and its impact on daily functioning.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 18
Healthy Volunteers: f
View:

• Patients aged between 5 and 18 years (inclusive) (Piaget's concrete operational stage to be able to complete the self-assessment questionnaires)

• Patients who underwent amputation before the age of 15 for girls and 16 for boys (average age of completion of lower limb growth)

• Patients who have not undergone surgery on the amputated limb for at least one year (to avoid bias, as any surgery involving incision can cause temporary neuropathic pain unrelated to the amputation)

• Have obtained the signature of the non-objection form by both parents/legal guardians

• Have obtained the child's consent (verbal consent but recorded)

• Be affiliated with a health insurance plan.

Locations
Other Locations
France
Hôpitaux Paris Est Val-de-Marne - Centre de Référence des Malformations des Membres
RECRUITING
Saint-maurice
Contact Information
Primary
Auriane AS SLAMA
auriane.slama@ght94n.fr
+33143967556
Time Frame
Start Date: 2026-02-19
Estimated Completion Date: 2027-02-02
Participants
Target number of participants: 50
Treatments
Pediatric limb amputation cohort
This cohort includes children and adolescents aged 5 to 18 years who underwent limb amputation during childhood and are followed at a specialized pediatric limb anomaly referral center.~Participants are evaluated at a single time point using retrospective medical record data and standardized questionnaires administered during routine follow-up visits, without any modification of standard clinical care.
Related Therapeutic Areas
Sponsors
Leads: Hopitaux de Saint-Maurice

This content was sourced from clinicaltrials.gov