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Effect of Vagus Nerve Stimulation on Pain Intensity, Nerve Conduction Studies and Functional Outcomes in Diabetic Peripheral Neuropathy Patients

Status: Recruiting
Location: See location...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To evaluate the efficacy of vagus nerve stimulation in reducing neuropathic pain, symptom severity, electrophysiological studies and functional outcomes in patients with diabetic peripheral neuropathy.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 60
Healthy Volunteers: f
View:

• Thirty patients diagnosed with diabetic neuropathy of both genders.

• Age range between 45 and 60 years.

• Presence of numbness and/or pain in the feet with no other identifiable cause.

• Pain characterized as stabbing, electric shock-like, or burning in nature.

• Presence of glove-stocking sensory changes and abnormal sensations in the distal lower limbs.

• Ability to ambulate independently without assistance.

• Patients under full medical control.

• Hemoglobin A1c levels ranging from 6.5% to 7%.

• History of diabetes mellitus for more than 5 years.

Locations
Other Locations
Egypt
outpatient clinic, faculty of physical therapy, Horus university
RECRUITING
Damietta
Contact Information
Primary
Hoda Mamdouh nematallah, assisstant lecturer
hmamdouh@horus.edu.eg
01096551775
Time Frame
Start Date: 2026-01-01
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 40
Treatments
Experimental: Transcutaneous Vagus nerve stimulation
Patients will receive the same traditional physical therapy as in traditional physical therapy group in addition to 30 min of transcutaneous auricular vagus nerve stimulation 5 sessions per week for 6 weeks.
Active_comparator: traditional physical therapy
Patients will receive 30 min of traditional physical therapy, and 30 min of placebo Non-Invasive vagus nerve stimulation, 5 sessions per week for 6 weeks
Sponsors
Leads: Cairo University

This content was sourced from clinicaltrials.gov