Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes: PROMISE-Lung Study

Status: Recruiting
Location: See all (17) locations...
Study Type: Observational
SUMMARY

This project aims to collect detailed clinical data, blood samples, and patient-reported outcomes from 2,600 lung transplant candidates, donors, and recipients at Lung Transplant Centers. The goal is to create a robust resource for various research objectives, including studying the impact of variations in donor and medical practices on clinical outcomes. The project also seeks to identify serum biomarkers associated with or predictive of specific post-transplant complications and conditions.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Able to understand and provide informed consent

• ≥ 18 years of age at the time of written informed consent

• Anticipated listing or listed for a single or bilateral cadaveric donor lung transplant or having received a lung transplant within 30 days

⁃ Participants undergoing repeat lung transplantation or multi-organ transplantation are eligible if they meet the inclusion/exclusion criteria.

Locations
United States
California
University of California Los Angeles
RECRUITING
Los Angeles
University of California at San Francisco
RECRUITING
San Francisco
Florida
University of Miami
RECRUITING
Miami
Massachusetts
Brigham and Womens Hospital
RECRUITING
Boston
Maryland
Johns Hopkins University
RECRUITING
Baltimore
Michigan
University of Michigan
RECRUITING
Ann Arbor
Minnesota
University of Minnesota
RECRUITING
Minneapolis
North Carolina
Duke University Medical Center
RECRUITING
Durham
New York
Columbia University
RECRUITING
New York
New York University
RECRUITING
New York
Pennsylvania
University of Pennsylvania
RECRUITING
Philadelphia
University of Pittsburgh Medical Center
RECRUITING
Pittsburgh
Tennessee
Vanderbilt University Medical Center
RECRUITING
Nashville
Virginia
Inova Fairfax Hospital
RECRUITING
Falls Church
Washington
University of Washington
RECRUITING
Seattle
Wisconsin
University of Wisconsin Hospital and Clinics
RECRUITING
Madison
Other Locations
Canada
University Health Network
RECRUITING
Toronto
Contact Information
Primary
Allyn Damman
allyn.damman@duke.edu
919-259-4414
Backup
Carl Schuler, RN
carl.schuler@duke.edu
919-695-2721
Time Frame
Start Date: 2024-09-03
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 2600
Treatments
Lung transplant donors and recipients
Lung transplant donors and adult (18 years and up) lung transplant candidates and recipients
Related Therapeutic Areas
Sponsors
Leads: Duke University
Collaborators: National Heart, Lung, and Blood Institute (NHLBI), University of Pennsylvania

This content was sourced from clinicaltrials.gov