Cellular Markers During a Non-tuberculous Mycobacterial Respiratory Infection, Treated or Untreated, in Patients With Cystic Fibrosis
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
This study evaluates a diagnostic serological test for Non-Tuberculous Mycobacteria (NTM) infection in cystic fibrosis patients by measuring T cell response. It aims to highlight a dynamic response associated to the pathogen's presence. This multicenter case-control study involves two populations, providing a better understanding of the circulating T-IFNγ-MNT response in these patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patient ≥18 years
• Patient previously included in the CIMeNT study
• Patient with a confirmed diagnosis of cystic fibrosis regardless of CFTR genotype
• Patient affiliated to the social security system
• Patient registered in the French Cystic Fibrosis Registry
• Adult patient capable of spontaneous expectoration or after induction
Locations
Other Locations
France
CHU de Montpellier - Hôpital Arnaud de Villeneuve
RECRUITING
Montpellier
Contact Information
Primary
Raphael CHIRON, MD
r-chiron@chu-montpellier.fr
0467336115
Backup
Jean-Louis HERRMANN, Pr
jean-louis.herrmann@aphp.fr
0147104470
Time Frame
Start Date: 2024-09-17
Estimated Completion Date: 2026-09-17
Participants
Target number of participants: 76
Treatments
Case group MNT +
Cystic fibrosis patients with positive serology and positive culture
Control group MNT -
Cystic fibrosis patients with negative serology and negative culture
Related Therapeutic Areas
Sponsors
Collaborators: Hôpital Cochin, Cystic Fibrosis Foundation
Leads: University Hospital, Montpellier