Comparison of Efficacy of Methotrexate vs Apremilast in Moderate to Severe Plaque Psoriasis
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
This study aims to compare efficacy of methotrexate vs apremilast in the management of chronic plaque psoriasis.Given the high prevalence of psoriasis in Pakistan and the significant psychological impact on patients, particularly in Peshawer,this study will provide valuable insights into optimal treatment strategies.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: t
View:
• Patients having age between 18-60 years of either gender Diagnosed with moderate to severe plaque psoriasis (PASI ≥10) No prior systemic therapy in past 3 months.
Locations
Other Locations
Pakistan
MTI-HMC Peshawar
RECRUITING
Peshawar
Contact Information
Primary
Filza Ajmal, FCPS part 2
binteajmal1996@gmail.com
+923008179226
Backup
Ghafoor Ullah
dr_ghafoorullah@yahoo.com
923335939818
Time Frame
Start Date: 2025-12-25
Estimated Completion Date: 2026-06-25
Participants
Target number of participants: 106
Treatments
Experimental: Methotrexate
This group will recieve methotrexate 10-25mg once weekly for 3 months,
Experimental: Apremilast
This group will recieve apremilast 30mg BD for 3 months.
Related Therapeutic Areas
Sponsors
Leads: Syeda Sana Zaman